Nonmetastatic nephrogenic hepatosplenomegaly and epilepsy.

Multiple myeloma with hepatosplenomegaly.

1Assistant Professor, Internal Medicine; 2Assistant Professor, Pathology; 3Head of Department of Critical Care; Military Hospital, Trivandrum Received: 22.07.2011; Accepted: 10.08.2013 Sir, T e C a s e r e p o r t “ M u l t i p l e m y e l o m a p r e s e n t i n g w i t h hepatosplenomagaly”1 was interesting and we would l ike to o f fer these comments 1. Peripheral blood smear giving a clue t...

An Unusual Case of Hepatosplenomegaly

Rash and hepatosplenomegaly in a newborn

A newborn male infant, with an estimated gestational age of 35weeks, was born via spontaneous vaginal delivery to a 28year-old mother, who presented in active labour with a macular rash on her hands and feet noted at the time of delivery, as shown in Fig. 1(c–e). Maternal history was significant for illicit drug use and scant prenatal care, without thorough serological evaluation performed prio...

An infant with seizures, rash, and hepatosplenomegaly.

(See pages 451–2 for the Photo Quiz) Figure 2. Scalp of the infant, showing crusted erythematous erosion following a ruptured bullae. Figure 1. Scaly, erythematous erosions with collaretes of crust and numerous bullae covering the entire lower limbs of the neonate. Diagnosis: congenital syphilis. The infant's rapid plasma reagin test was reactive at a titer of 1:256 dilutions; a Treponema palli...

An Unusual Case of Hepatosplenomegaly with Cytopenia

Autoimmune lymphoproliferative syndrome (ALPS) is a rare, inherited disorder of immune dysregulation secondary to defective lymphocyte apoptosis. This leads to uninhibited proliferation of lymphoid tissue manifesting with lymphadenopathy, hepatosplenomegaly, autoimmune cytopenia, and an increased risk of lymphoid malignancy. We report a twoyearold boy with fever, generalized lymphadenopathy, he...